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Long-term angiographic outcome of stent-assisted coiling compared to nonassisted coiling of intracranial saccular aneurysms

机译:与无辅助盘绕颅内囊状动脉瘤相比,支架辅助盘绕的长期血管造影结果

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摘要

Aim To compare angiographic result at long-term followup,and rates of progressive occlusion, recurrence, and retreatmentof stent-assisted coiled (SAC) and non-assistedcoiled (NAC) intracranial saccular aneurysms.Methods Retrospective evaluation of department recordsidentified 260 patients with 283 saccular intracranial aneurysmswho had long-term angiographic follow-up (morethan 12 months) and were successfully treated with SAC(89 aneurysms) or NAC (194 aneurysms) at the UniversityHospital Center Zagreb from June 2005 to July 2012. Initialand control angiographic results in both groups weregraded using Roy/Raymond scale, converted to descriptiveterms, and the differences between them were evaluatedfor statistical significance. A multivariate analysis wasperformed to identify factors related to progression of aneurysmocclusion and recurrence at follow-up, and thoserelated to aneurysm retreatment.Results There were more progressively occluded aneurysmsin SAC group (38 of 89 aneurysms, 42.7%) than inNAC group (46 of 194, 23.7%) (P = 0.002), but there wereno significant differences in the rates of recanalization, regrowth,and stable result. Multivariate logistic regressionidentified the use of stent as the most important factor associatedwith progressive occlusion (P = 0.015, odds ratio2.22, 95% confidence interval 1.17-4.21), and large aneurysmsize and posterior circulation location as most predictiveof aneurysm recurrence and retreatment.Conclusion The use of stent is associated with delayed occlusionof initially incompletely coiled aneurysms duringfollow-up, but does not reduce the rate of recurrence andretreatment compared to coiling alone. Long-term angiographicfollow-up is needed for both SAC and NAC aneurysms.
机译:目的比较长期随访的血管造影结果,以及支架辅助盘绕(SAC)和非辅助盘绕(NAC)颅内囊动脉瘤的渐进性闭塞,复发和再治疗率。方法回顾性评估部门记录,确定260例283例患者颅内动脉瘤患者进行了长期的血管造影随访(超过12个月),并于2005年6月至2012年7月在萨格勒布大学医院中心成功地用SAC(89个动脉瘤)或NAC(194个动脉瘤)进行了治疗。两组的初始和对照血管造影结果使用Roy / Raymond量表对数据进行分级,转换为描述性术语,并对它们之间的差异进行统计学意义评估。进行多因素分析以找出与动脉瘤闭塞进展和随访时复发有关的因素,以及与动脉瘤再治疗有关的因素。结果SAC组(89例动脉瘤中的38例,42.7%)比NAC组(194例中的46例)闭塞的发生率更高(23.7%)(P = 0.002),但再通率,再生长率和稳定结果无显着差异。多元logistic回归确定支架的使用是与进行性闭塞相关的最重要因素(P = 0.015,比值比2.22,95%置信区间1.17-4.21),大动脉瘤大小和后循环位置是最能预测动脉瘤复发和再治疗的结论。支架的使用与随访期间最初不完全盘绕的动脉瘤的延迟闭塞有关,但与单独盘绕相比,并没有降低复发率和再治疗率。 SAC和NAC动脉瘤均需要长期血管造影随访。

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